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Angiogenesis and Tumor Progression in Neuroendocrine Digestive Tumors
Journal of Surgical Research, 05/14/09
Poncet G et al. - The experimental data concur with clinical findings to suggest that in well differentiated digestive neuroendocrine tumors angiogenesis is disconnected from tumor progression: the development of a highly vascular tumor microenvironment is correlated with VEGF secretion but is not associated with invasive and metastatic properties; it must therefore be regarded as an indirect marker of differentiation.
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