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See Latest ArticlesRecombinant Thrombin: Safety and Immunogenicity in Burn Wound Excision and Grafting
Journal of Burn Care & Research, 05/14/09
Greenhalgh DG et al. - None of the antibodies neutralized native human thrombin. In excised burn wounds, hemostasis at 20 minutes was achieved in 91.5% of patients and skin graft survival was excellent. There was a low rate of antibodies to rThrombin at baseline and a low rate of anti-rThrombin antibody formation at day 29. rThrombin was well tolerated when administered with a pump spray.
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