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See Latest ArticlesS-nitrosylation of caspase-3 is the mechanism by which adhesion fibroblasts manifest lower apoptosis
Wound Repair and Regeneration, 03/23/09
Jiang ZL et al. - The authors conclude that S-nitrosylation of caspase-3 is the reason for its decreased activity and subsequent decrease in apoptosis of adhesion fibroblasts. The mechanism by which caspase-3 S-nitrosylation occurs is not fully understood. However, the role of hypoxia in the formation of peroxynitrite via superoxide production may suggest a possible mechanism.
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