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The role of sentinel node biopsy in ductal carcinoma in situ of the breast
European Journal of Surgical Oncology, 09/08/08

Polom K et al. – Sentinel node biopsy (SNB) for diagnosis in ductal carcinoma in situ (DCIS) remains controversial due to few cases of axillary lymph node metastases; the related clinical challenge is a primary diagnosis of DCIS with invasive components on mammotomic biopsy

Methods

Study of the diagnostic value of sentinel nodes in female pts with primary DCIS using core needle stereotactic biopsy
Core needle biopsy for diagnosis of DCIS in 216 pts
SNB to determine lymph node involvement for 183 pts
Axillary lymphadenectomy for pts with metastases to the sentinel node

Results

Of 183 pts, 10 (5.5%) had metastases to sentinel lymph node
Of these 10 pts, invasive ductal carcinoma in 6 cases (3.5%); 1 case (0.5%) of invasive lobular carcinoma
DCIS with metastases to sentinel lymph nodes as final diagnosis for 3 pts (1.5%): 2 DCIS; 1 DCIS with microinvasion
Axillary lymphadenectomy for pts with abnormal SNB showed other axillary lymph node involvement in 4 pts

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