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See Latest ArticlesPhase I dose-finding study of weekly docetaxel followed by flavopiridol for patients with advanced solid tumors
Clinical Cancer Research, 10/04/07
Fornier, M.N., et al. - Treatment with weekly, sequential docetaxel followed by flavopiridol, a cyclin-dependent kinase inhibitor, is safe and effective; flavopiridol enhances the effects of docetaxel Methods 27 patients with various tumors were enrolled (pancreas, breast, and ovarian) Docetaxel (35 mg/m2) followed 4h later by escalating doses of flavopiridol (20-80 mg/kg2) was administered for 3 wks of each 4 wk cycle Results CR was observed in 1 patient with pancreatic cancer PR was observed in 1 patient with pancreatic, 2 patients with breast, and 1 patient with ovarian cancer Stable disease occurred in 10 patients One dose-limiting toxicity occurred at 70 mg/kg2 and 1 at 80 mg/kg2
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Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement
Annals of Internal Medicine, 11/17/09
Screening for Breast Cancer: An Update for the U.S. Preventive Services Task Force
Annals of Internal Medicine, 11/17/09
Radiation therapy and tamoxifen after breast-conserving surgery: Updated results of a 2×2 randomised clinical trial in patients with low risk of recurrence
European Journal of Cancer, 11/05/09
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