Evaluation of aFGF/bFGF and FGF Signaling Pathway in the Wall of Varicose Veins Kowalewski R et al. - Overexpressed aFGF in the wall of varicose veins via FGFR and the MAP kinase pathway may influence expression of enzymes involved in extracellular matrix metabolism and play a role in vein wall remodeling, as well as in the disease pathogenesis. [more...]