Cancer in obese women: Potential protective impact of bariatric surgery
McCawley GM et al. - Breast and endometrial cancers remain the most common types in obese women and may occur at young ages; bariatric surgery may decrease cancer development in obese women. Methods- Study to report on:
- types of cancer in morbidly obese women undergoing bariatric surgery and
- compare these with types of cancer in obese women w/o surgery
- Bariatric surgery database identified women who underwent operations between 1990-2006 at the Univ. of Virginia
- Morbidly obese pts not undergoing bariatric surgery were used for comparison
Results- 1,482 women had bariatric surgery, 3.6% were diagnosed with cancer
- Most common cancer site was the breast followed by the endometrium and the cervix
- Mean age at cancer diagnosis was 39.4 yrs
- Most cancers were diagnosed before the bariatric surgery
- Bariatric surgery pts with cancer were older than noncancer pts at time of surgery
- Compared to obese women who had not undergone bariatric surgery, the surgery pts had fewer cancers, were younger, and were younger at cancer diagnosis
- Most frequent cancers in the control obese women: endometrial, ovarian, and breast cancer
- Both groups of obese women with endometrial, breast, ovarian, and colorectal cancers were younger at diagnosis compared with Virginia Cancer Registry means
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