COX-2 mRNA expression in esophageal squamous cell carcinoma (ESCC) and effect by NSAID Liu, X., et al. - COX-2 mRNA expression is a frequent phenomenon in human ESCC tissue samples and plays an important role in the carcinogenesis of ESCC. NSAID may be useful in the chemoprevention and therapy of human ESCC and its effects are likely to be mediated by modulating COX-2 activity [more...]