Upper gastrointestinal investigations before gastric banding
Surgical Endoscopy, 11/02/2009
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Bueter M et al. – Endoscopy and pH monitoring do not predict outcome for gastric banding and therefore have no relevance in the selection of patients for gastric banding. Patients with an incompetent LES shown by manometry had a
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Gastric Band Placement for Obesity is Not Associated With Increased Urinary Risk of Urolithiasis Compared to Bypass
The Journal of Urology, 10/19/2009
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Penniston KL et al. – The study confirms the risk of urinary stones following the Roux–en–Y gastric bypass procedure as a result of hyperoxaluria, low urine volume ... and hypocitraturia. Those with gastric banding placement had low urine volumes. Future studies should elucidate the effect of nutrition and/or pharmacological therapy on stone risk of both surgeries as their incidence increases.
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Weight Loss Through Gastric Banding: Effects on TSH and Thyroid Hormones in Obese Subjects With Normal Thyroid Function
Obesity, 10/20/2009
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Dall'Asta C et al. – Albumin and cholesterol levels remained steady, while triglycerides, insulin, and homeostasis model assessment of insulin resistance decreased, and ... lipoprotein–cholesterol increased. These changes, however, do not modify TSH, letting us to hypothesize that the changes are due to a decrease of D1 and D2 deiodinase activities.
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The effects of conservative and surgical treatment for obesity on gastro-oesophageal reflux disease
Alimentary Pharmacology and Therapeutics, 11/03/2009
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effect is likely to be found after bariatric surgery, especially after Roux–en–Y gastric bypass. Future studies need to elucidate for which GERD patients laparoscopic adjustable gastric banding might have a beneficial effect and how they can be identified preoperatively
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Long-term effects of laparoscopic sleeve gastrectomy, gastric bypass, and adjustable gastric banding on type 2 diabetes
Surgical Endoscopy, 11/02/2009
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Abbatini F et al. – All three bariatric procedures are effective in treating diabetes, with a 3–year follow–up evaluation showing an effect that lasts. The AGB
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Laparoscopic Adjustable Silicone Gastric Banding vs Laparoscopic Vertical Banded Gastroplasty in Morbidly Obese Patients: Long-Term Results of a Prospective Randomized Controlled Clinical Trial
Obesity Surgery, 10/29/2009
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Scozzari G et al. – This study demonstrates that in a carefully selected group of patients, LVBG
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Microwave coagulation versus sclerotherapy after band ligation to prevent recurrence of high risk of bleeding esophageal varices in Child-Pughs A and B patients
Journal of Gastroenterology, 10/06/2009
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Monici LT et al. – Application of MC to esophageal varices after band ligation is safe. The post–MC recurrence rate may be ... treatment of EBL and EIS. The presence of gastric varices increases the risk of esophageal variceal recurrence.
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Changes in Quality of Life After Balloon Treatment Followed by Gastric Banding in Severely Obese Patients—The Use of Two Different Quality of Life Questionnaires
Obesity Surgery, 11/04/2009
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Rutten S et al. – The QOL improved substantially independent of changes in BMI. Because of the divergent outcomes of generic and
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CHD5 is down-regulated through promoter hypermethylation in gastric cancer
BMC: Journal of Biomedical Science, 10/26/2009
Wang X et al. – In this study, the involvement of CHD5 in gastric cancer was investigated , the second most common cancer worldwide. CHD5 was a TSG epigenetically down-regulated in gastric cancer. Methods- CHD5 expression in panel of gastric cancer cells ... PCR and bisulfite genome sequencing
- Effect of CHD5 on growth of gastric cancer cells tested by colony formation assay
Results- CHD5 expression down-regulated in all of gastric cancer cell lines used (100%, 7/7) and significantly restored after pharmacological ... gastric cancer cell lines and in majority of primary gastric carcinoma tissues examined (73%, 11/15)
- Ectopic expression of CHD5 in gastric cancer cells led to significant growth inhibition
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Promoter hypermethylation mediates downregulation of thiamine receptor slc19a3 in gastric cancer
Tumor Biology, 10/12/2009
Liua X et al. – SLC19A3 was epigenetically downregulated in gastric cancer. Methylation of SLC19A3 promoter could be a novel biomarker for early gastric cancer development Methods- Promoter hypermethylation ... downregulated in gastric cancer cell lines (71%, 5/7) and restored after pharmacological demethylation
Results- SLC19A3 (solute carrier family 19, member 3) found to be such a biomarker
- Hypermethylation of SLC19A3 promoter detected in gastric cancer cell lines (57 ... gastric carcinoma tissues (51%, 52/101) and precancerous lesion (intestinal metaplasia) tissues (32%, 8/25)
- Exogenous SLC19A3 expression caused growth inhibition of gastric cancer cells
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