Top central line Articles in Surgery

Validation of Statewide Surveillance System Data on Central Line-Associated Bloodstream Infection in Intensive Care Units in Australia
Infection Control and Hospital Epidemiology, 10/08/2009

McBryde ES et al. – The agreement between the reporting of central line–associated BSI and the gold standard application of definitions was ... more than half of central line–associated BSIs may be missed in Victorian public hospitals. [more...]

Concurrence between Interpupillary Line and Tangent to the Incisal Edge of the Upper Central Incisor Teeth
Journal of Esthetic and Restorative Dentistry, 10/05/2009

Malafaia FM et al. – Dento–facial harmony is essential to obtain adequate esthetics and a successful treatment. Therefore, the aim of the present study was to analyze the ... lines, one along the pupils and another along the incisal edge of the upper central incisor teeth of 102 dental students distributed across five Brazilian dental schools. Regardless of gender, there is a correlation between the pupils and the tangent with the incisal edge of the maxillary central ... incisors. [more...]

Ultrasound-guided peripheral intravenous access in the intensive care unit
Journal of Critical Care, 10/22/2009

al. – In intensive care unit patients who do not require central venous lines, ultrasound–guided PIV access can have a high placement success rate and can result in fewer central line days and/or less reliance on central venous catheters for access–only purposes. [more...]

North Central Cancer Treatment Group (NCCTG) N0432: Phase II trial of docetaxel with capecitabine and bevacizumab as first-line chemotherapy for patients with metastatic breast cancer
Annals of Oncology, 11/16/2009

Perez EA et al. – Docetaxel (T; Taxotere) with capecitabine (X) is active against metastatic breast cancer (MBC ... bevacizumab (BV) has demonstrated efficacy with taxanes in the first-line setting. This study was conducted to assess the safety and efficacy of TX-BV in patients with MBC. TX-BV demonstrated significant activity; dose modifications were required to manage drug-related toxic effects. Methods ... Patients received first-line bevacizumab 15 mg/kg and docetaxel 75 mg/m2 on day 1 and capecitabine 825 mg/m2 twice per day on days 1–14 every 21 days Primary and secondary end points were tumor RR, OS, PFS, and toxicity Results Total of 45 assessable patients [more...]

Therapeutic efficacy of chloroquine and sequence variation in pfcrt gene among patients with falciparum malaria in central India
Tropical Medicine & International Health, 11/13/2009

Bharti PK et al. – The high rate of treatment failure in the present study clearly indicates the need to reassess the use of CQ as first–line antimalarial therapy in central India. This is supported by the presence of mutant [more...]

A survey of post-craniotomy analgesia in British neurosurgical centres: time for perceptions and prescribing to change?
British Journal of Neurosurgery, 10/01/2009

Kotak D et al. – 31 adult neurosurgical units were surveyed. Twenty three percent (7 units) had a standardized analgesic regime/protocol and 65% routinely assessed pain ... codeine phosphate or dihydrocodeine (22 units) as the first line opioid the other 30% using morphine (9 units). Forty two percent (13 units) used tramadol; patient controlled analgesia was used in 3 units. Regular paracetamol was prescribed in all but five (16%) units. Fifty two percent of units (16 ... in all but two units. Cyclizine was the first–line anti–emetic in 45% of the units, ondansetron in 29% and metoclopramide in 16%. There is currently no consensus on pain management after craniotomy in neurosurgical centres in the UK. Until there are sufficiently powered randomized [more...]

Isolation and Characterization of Omental Adipose Progenitor Cells in Children: A Potential Tool to Unravel the Pathogenesis of Metabolic Syndrome
Hormone Research, 10/27/2009

lines from omental adipose tissue of children may allow future investigations aimed at unraveling whether fetal programming of adipogenesis is responsible for the pathogenesis of the metabolic syndrome that develops during adulthood in subjects, born with low birth weight, typically showing central [more...]

The role of dopamine in bipolar disorder
Bipolar Disorders, 11/19/2009

Cousins DA et al. – Multiple lines of evidence, including data from pharmacological interventions and structural and functional magnetic resonance imaging studies, suggest that the dopaminergic system may play a central role in bipolar disorder. [more...]

Gemcitabine and carboplatin in the treatment of transitional cell carcinoma of the urothelium: a single centre experience and review of the literature
European Journal of Cancer Care, 11/18/2009

Hudson E et al. – There is now evidence suggesting that gemcitabine and cisplatin may be more efficacious, and until the appropriate ... first–line therapy. Gemcitabine and carboplatin is an effective alternative in those patients not deemed fit enough for cisplatin. [more...]

Temporal pattern of gene expression and histology of stress fracture healing
Bone, 11/03/2009

of RANKL indicates the importance of these factors in mediating directed remodelling of the fracture line. Dramatic, early upregulation of IL–6 and IL–11 demonstrate their central role in initiating signalling events for remodelling and stress fracture healing. [more...]