Antibiotics as First-line Therapy for Acute Appendicitis: Evidence for a Change in Clinical Practice
World Journal of Surgery, 05/17/2012
Hansson J et al. – This population–based study confirms previous results of randomized studies. Antibiotic treatment can be offered as the first–line therapy to a majority of unselected patients with acute appendicitis without medical drawbacks other than the unknown risk for long–term relapse, which must be weighed against the unpredicted but well–known risk for serious major complications following surgical intervention.