Surgery - Basic Science/Genetics News & Articles

MDLinx Surgery is your ultimate resource for the latest General Surgery and subspecialty surgery news articles published in over 2,000 peer-reviewed medical journals and popular press. Our diligent team of medical editor’s rank sort and summarize Surgery news articles with topics ranging from: Cardiac Surgery, Critical Care, Vascular, Thoracic, Peds Surgery, Neurosurgery and much more. On this page you may also find bonus content that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read “ as well as clinical pearls taken from our Smartest Doc quiz competition.

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Articles

Latest (1) Full Text Articles (20)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Right papillary muscle sling: proof of concept and pilot clinical experience European Journal of Cardio-Thoracic Surgery, May 17, 2013 Review Article

Prior Articles

2 Desktop Transcriptome Sequencing From Archival Tissue to Identify Clinically Relevant Translocations American Journal of Surgical Pathology , May 15, 2013 Clinical Article

3 Persistent stapedial arteries in human: from phylogeny to surgical consequences Surgical and Radiologic Anatomy, May 14, 2013 Review Article

4 REG1A Expression Status Suggests Chemosensitivity Among Advanced Thoracic Esophageal Squamous Cell Carcinoma Patients Treated with Esophagectomy Followed by Adjuvant Chemotherapy Annals of Surgical Oncology, May 13, 2013 Clinical Article

5 Oral Nucleoside/Nucleotide Analogs Without Hepatitis B Immune Globulin After Liver Transplantation for Hepatitis B The American Journal of Gastroenterology, May 13, 2013 Review Article

6 Novel protease-based diagnostic devices for detection of wound infection Wound Repair and Regeneration, May 10, 2013 Review Article

7 Properdin and Factor H: Opposing Players on the Alternative Complement Pathway See-Saw Frontiers in Immunology, May 7, 2013 Review Article

8 808nm Wavelength Light Induces a Dose-Dependent Alteration in Microglial Polarization and Resultant Microglial Induced Neurite Growth Lasers in Surgery and Medicine, May 6, 2013 Clinical Article

9 STAT3 Pathway Is Activated in ALK-positive Large B-cell Lymphoma Carrying SQSTM1-ALK Rearrangement and Provides a Possible Therapeutic Target American Journal of Surgical Pathology , May 3, 2013 Clinical Article

10 Diffuse Leptomeningeal Neuroepithelial Tumor: 9 Pediatric Cases With Chromosome 1p/19q Deletion Status and IDH1 (R132H) Immunohistochemistry American Journal of Surgical Pathology , May 3, 2013 Clinical Article

11 Osteopontin Up-Regulates Critical Epithelial-Mesenchymal Transition Transcription Factors to Induce an Aggressive Breast Cancer Phenotype Journal of the American College of Surgeons, May 2, 2013 Clinical Article

12 EWSR1-CREB3L1 Gene Fusion: A Novel Alternative Molecular Aberration of Low-grade Fibromyxoid Sarcoma American Journal of Surgical Pathology , May 2, 2013

13 Plasmacytoid Dendritic Cells: No Longer an Enigma and Now Key to Transplant Tolerance? American Journal of Transplantation, May 1, 2013 Review Article

14 Mid-term outcomes following endovascular re-intervention for iliac artery in-stent restenosis Catheterization and Cardiovascular Interventions, May 1, 2013 Clinical Article

15 Epithelioid GBMs Show a High Percentage of BRAF V600E Mutation American Journal of Surgical Pathology , May 1, 2013 Clinical Article

16 Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery Full Text BMC Cancer, April 30, 2013 Review Article

17 High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease American Heart Journal, April 30, 2013 Clinical Article

18 Stapled versus hand-sewn anastomoses in emergency general surgery: A retrospective review of outcomes in a unique patient population The Journal of Trauma and Acute Care Surgery, April 29, 2013 Continuing Medical Education Evidence Based Medicine Review Article

19 Spontaneous rupture of an advanced pancreatoblastoma: Aberrant RASSF1A methylation and CTNNB1 mutation as molecular genetic markers Journal of Pediatric Surgery, April 29, 2013

20 Life after near death: Long-term outcomes of emergency department thoracotomy survivors The Journal of Trauma and Acute Care Surgery, April 29, 2013 Clinical Article

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Clinical Pearls in Surgery

Surgery is the cornerstone of treatment for advanced acne inversa
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After having bariatric surgery, sleep duration increases significantly

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Highlights in Surgery

Epidural anesthesia reduces post-CABG pain

As published in the Journal of Cardiac Surgery, thoracic epidural anesthesia (TEA) plus general anesthesia (GA) is superior to GA alone in managing post-operative CABG pain. Forty patients undergoing elective CABG were randomized to receive TEA (0.25% bipivacaine [10-20 mg/h]) intra-operatively and for 24 h post-operatively plus GA or GA alone. Post-operative pain at rest and with coughing was significantly less for up to 1 month post-operatively in the TEA + GA group compared to the GA alone group. Furthermore, analgesic use, mechanical ventilation time, ICU stay time, and hospital stay time were reduced in the TEA + GA group compared to the GA alone group.

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NT-proBNP predicts outcome following emergent surgery

As published in the British Journal of Anaesthesia, measurement of N-terminal pro B-type natruiretic peptide (NT-proBNP) pre- and post-operatively predicts outcome in patients > 50 years of age (n=297) undergoing emergent non-cardiac surgery. A pre-operative NT-proBNP > 725 pg/ml was associated with a 4.8-fold RR of non-fatal MI, acute heart failure, or death between surgery and the 3-year post-operative follow up. Similarly, a post-operative NT-proBNP > 1600 pg/ml was associated with a 4.0-fold RR of non-fatal MI, acute heart failure, or death between surgery and the 3-year post-operative follow up. A pre-operative NT-proBNP > 1740 pg/ml was associated with a 6.9 RR for major adverse cardiac events during the post-operative hospital stay.

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Increased risk of skin cancer in RCC treated with multikinase inhibitors

As published in Dermatologic Surgery, RCC patients (n=69) treated with multikinase inhibitors are at increased risk for squamous cell carcinomas and basal cell carcinomas. After a median treatment of 13.5 months, 13.5% and 6.3% of patients treated with sorafenib and sunitinib developed skin cancer, respectively.

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Surgery - Basic Science/Genetics News & Articles

Articles

Prior Articles

Clinical Pearls in Surgery

Highlights in Surgery

Epidural anesthesia reduces post-CABG pain

NT-proBNP predicts outcome following emergent surgery

Increased risk of skin cancer in RCC treated with multikinase inhibitors

Most Popular Surgery Articles

Other Topics in Surgery