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Surgery - Basic Science/Genetics News Articles

MDLinx Surgery is your ultimate resource for the latest General Surgery and subspecialty surgery news articles published in over 2,000 peer-reviewed medical journals and popular press. Our diligent team of medical editor’s rank sort and summarize Surgery news articles with topics ranging from: Cardiac Surgery, Critical Care, Vascular, Thoracic, Peds Surgery, Neurosurgery and much more. On this page you may also find bonus content that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read “ as well as clinical pearls taken from our Smartest Doc quiz competition.

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Latest (1) Full Text Articles (20)
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 The effect of centrifugation condition on mature adipocytes and adipose stem cell viability Annals of Plastic Surgery, April 23, 2014    Clinical Article

Prior Articles

2 An unanticipated role for survivin in organ transplant damage American Journal of Transplantation, April 22, 2014    Clinical Article

3 Autologous dendritic cells prolong allograft survival through Tmem176b-dependent antigen cross-presentation American Journal of Transplantation, April 22, 2014    Clinical Article

4 Calots triangle: proposal to rename it as Calots region and the concept of ducto-arterial plane Indian Journal of Surgery, April 18, 2014    Clinical Article

5 Morphology, localization, and patterns of ghrelin-producing cells in stomachs of a morbidly obese population Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, April 18, 2014    Clinical Article

6 Neuropilin 1 expression in human aortas, coronaries and the main bypass grafts European Journal of Cardio-Thoracic Surgery, April 18, 2014    Clinical Article

7 Platelet adhesion to polyurethane urea under pulsatile flow conditions Artificial Organs, April 17, 2014    Review Article

8 Direct expansion of chondrocytes in a dynamic three-dimensional culture system: Overcoming dedifferentiation effects in monolayer culture Artificial Organs, April 17, 2014    Clinical Article

9 The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: A pilot study Annals of Surgical Oncology, April 15, 2014    Clinical Article

10 Altered postprandial responses in gastric myoelectrical activity and cardiac autonomic functions in healthy obese subjects Obesity Surgery, April 15, 2014    Review Article

11 Surgeons are overlooking post-discharge complications: A prospective cohort study World Journal of Surgery, April 11, 2014    Clinical Article

12 Cotransplantation with myeloid-derived suppressor cells protects cell transplants: A crucial role of inducible nitric oxide synthase Transplantation, April 10, 2014    Clinical Article

13 Association between TERT rs2736100 polymorphism and risk of glioma Journal of Surgical Research, April 7, 2014    Clinical Article

14 Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis Journal of Surgical Research, April 4, 2014    Review Article

15 Polymorphisms of genes involved in the hypoxia signaling pathway and the development of abdominal aortic aneurysms or large-artery atherosclerosis Journal of Vascular Surgery, April 3, 2014    Clinical Article

16 Utility of gene expression profiling score variability to predict clinical events in heart transplant recipients Transplantation, April 2, 2014    Clinical Article

17 Lipopolysaccharide mediated enhancement of zymosan phagocytosis by RAW 264.7 macrophages is independent of opsonins, laminarin, mannan and complement receptor 3 Journal of Surgical Research, April 2, 2014    Clinical Article

18 Digital imaging analysis to assess scar phenotype Wound Repair and Regeneration, March 28, 2014    Review Article

19 Whole-genome sequencing of an aggressive BRAF wild-type papillary thyroid cancer identified EML4-ALK translocation as a therapeutic target World Journal of Surgery, March 27, 2014

20 MUTYH-associated colorectal cancer and adenomatous polyposis Surgery Today, March 26, 2014    Review Article

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Clinical Pearls in Surgery

Highlights in Surgery

Epidural anesthesia reduces post-CABG pain

As published in the Journal of Cardiac Surgery, thoracic epidural anesthesia (TEA) plus general anesthesia (GA) is superior to GA alone in managing post-operative CABG pain. Forty patients undergoing elective CABG were randomized to receive TEA (0.25% bipivacaine [10-20 mg/h]) intra-operatively and for 24 h post-operatively plus GA or GA alone. Post-operative pain at rest and with coughing was significantly less for up to 1 month post-operatively in the TEA + GA group compared to the GA alone group. Furthermore, analgesic use, mechanical ventilation time, ICU stay time, and hospital stay time were reduced in the TEA + GA group compared to the GA alone group.

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NT-proBNP predicts outcome following emergent surgery

As published in the British Journal of Anaesthesia, measurement of N-terminal pro B-type natruiretic peptide (NT-proBNP) pre- and post-operatively predicts outcome in patients > 50 years of age (n=297) undergoing emergent non-cardiac surgery. A pre-operative NT-proBNP > 725 pg/ml was associated with a 4.8-fold RR of non-fatal MI, acute heart failure, or death between surgery and the 3-year post-operative follow up. Similarly, a post-operative NT-proBNP > 1600 pg/ml was associated with a 4.0-fold RR of non-fatal MI, acute heart failure, or death between surgery and the 3-year post-operative follow up. A pre-operative NT-proBNP > 1740 pg/ml was associated with a 6.9 RR for major adverse cardiac events during the post-operative hospital stay.

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Increased risk of skin cancer in RCC treated with multikinase inhibitors

As published in Dermatologic Surgery, RCC patients (n=69) treated with multikinase inhibitors are at increased risk for squamous cell carcinomas and basal cell carcinomas. After a median treatment of 13.5 months, 13.5% and 6.3% of patients treated with sorafenib and sunitinib developed skin cancer, respectively.

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Most Popular Surgery Articles

Last month's top read Top Articles of 2013

1 The autodigestion hypothesis for shock and multi-organ failure Annals of Biomedical Engineering, March 7, 2014

2 Hb-egf promotes cell migration and adhesion via focal adhesion kinase Journal of Surgical Research, March 19, 2014    Review Article

3 MUTYH-associated colorectal cancer and adenomatous polyposis Surgery Today, March 26, 2014    Review Article

4 Analysis of the abdominal musculo-aponeurotic anatomy in rectus diastasis: comparison of CT scanning and preoperative clinical assessment with direct measurement intraoperatively Hernia, February 13, 2014

5 Exposing endothelial cells to tumor necrosis factor-α and peripheral blood mononuclear cells damage endothelial integrity via interleukin-1ß by degradation of vascular endothelial-cadherin Surgery, January 29, 2014

6 Autofluorescence of liver tissue and bile: Organ functionality monitoring during ischemia and reoxygenation Lasers in Surgery and Medicine, March 21, 2014

7 Genetic modifiers of obesity and bariatric surgery outcomes Seminars in Pediatric Surgery, February 19, 2014    Review Article

8 Digital imaging analysis to assess scar phenotype Wound Repair and Regeneration, March 28, 2014    Review Article

9 Characterisation of postoperative immune suppression by validated parameters in visceral surgery Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie, January 8, 2014

10 Therapeutic potential of transgenic mesenchymal stem cells engineered to mediate anti–HMGB1 activity: Targeting of colon cancer Journal of Surgical Research, March 14, 2014

Indexed Journals in Surgery: Surgery, Journal of the American College of Surgeons, Annals of Surgerymore

Other Topics in Surgery

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