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Surgery - Basic Science/Genetics News & Articles
MDLinx Surgery is your ultimate resource for the latest General Surgery and subspecialty surgery news articles published in over 2,000 peer-reviewed medical journals and popular press. Our diligent team of medical editor’s rank sort and summarize Surgery news articles with topics ranging from: Cardiac Surgery, Critical Care, Vascular, Thoracic, Peds Surgery, Neurosurgery and much more. On this page you may also find bonus content that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read “ as well as clinical pearls taken from our Smartest Doc quiz competition.
As an MDLinx member you can stay current in less than 5 minutes a day via newsletters that encompass a list of the top ranked Surgery articles delivered directly to your inbox. As a member you may also receive monthly updates about upcoming Surgery conferences, Category 1 & 2 CME opportunities, Market Research invitations and much more!
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Articles
Latest (2) Full Text Articles (20)901 Inhibition of Phosphatidylinositol 3-Kinase/Akt Signaling Suppresses Tumor Cell Proliferation and Neuroendocrine Marker Expression in GI Carcinoid Annals of Surgical Oncology, July 13, 2009
902 Prognostic role of myeloid cell leukemia-1 protein (Mcl-1) expression in human gastric cancer Journal of Surgical Oncology, July 8, 2009
903 Increased expression of hyaluronic acid binding protein 1 is correlated with poor prognosis in patients with breast cancer Journal of Surgical Oncology, July 7, 2009
904 Serum p53 Antibody as Tumor Marker for Follow-Up of Colorectal Cancer After Curative Resection Annals of Surgical Oncology, July 6, 2009
905 Regulation of Matrix Contraction in Chronic Venous Disease European Journal of Vascular and Endovascular Surgery, July 6, 2009
906 Matrix Metalloproteinase-2 Gene Variants and Abdominal Aortic Aneurysm European Journal of Vascular and Endovascular Surgery, July 6, 2009
907 Allospecific CD154+ T cells identify rejection-prone recipients after pediatric small-bowel transplantation Surgery, July 6, 2009
908 Neurosecurity: security and privacy for neural devices Full Text Neurosurgical Focus, July 2, 2009 Continuing Medical Education
909 Human cortical prostheses: lost in translation? Full Text Neurosurgical Focus, July 2, 2009 Continuing Medical Education
910 Comprehensive Analysis of the Clinical Significance of Inducing Pluripotent Stemness-Related Gene Expression in Colorectal Cancer Cells Annals of Surgical Oncology, July 1, 2009
911 T regulatory cells in xenotransplantation Xenotransplantation, July 1, 2009
912 A Case of Primary Synovial Sarcoma of the Thorax With a Variant SYT-SSX1 Fusion Transcript Full Text Annals of Thoracic Surgery, June 30, 2009
913 Soluble Human Leukocyte Antigen class I antigen and interleukin-12 in hepatectomized patients ANZ Journal of Surgery, June 29, 2009
914 IgG4-related Sclerosing Mastitis: Description of a New Member of the IgG4-related Sclerosing Diseases American Journal of Surgical Pathology , June 26, 2009
915 REG1A predicts recurrence in stage Ta/T1 bladder cancer European Journal of Surgical Oncology, June 26, 2009
916 Patterns of expression and function of the p75NGFR protein in pancreatic cancer cells and tumours European Journal of Surgical Oncology, June 26, 2009
917 Basal Cytokeratin and Epidermal Growth Factor Receptor Expression Are Not Predictive of BRCA1 Mutation Status in Women With Triple-negative Breast Cancers American Journal of Surgical Pathology , June 26, 2009
918 Selective Internal Radiation Therapy-induced Extrahepatic Injury: An Emerging Cause of Iatrogenic Organ Damage American Journal of Surgical Pathology , June 26, 2009
919 Critical Diagnoses in Surgical Pathology: A Retrospective Single-institution Study to Monitor Guidelines for Communication of Urgent Results American Journal of Surgical Pathology , June 26, 2009
920 Epithelioid-cell Myofibroblastoma of the Breast: Expanding the Morphologic Spectrum American Journal of Surgical Pathology , June 26, 2009
Clinical Pearls in Surgery
- Surgery is the cornerstone of treatment for advanced acne inversa
- Positive botulinum toxin type A response is a significant predictor of migraine surgery success.
- After having bariatric surgery, sleep duration increases significantly
Highlights in Surgery
Epidural anesthesia reduces post-CABG pain
As published in the Journal of Cardiac Surgery, thoracic epidural anesthesia (TEA) plus general anesthesia (GA) is superior to GA alone in managing post-operative CABG pain. Forty patients undergoing elective CABG were randomized to receive TEA (0.25% bipivacaine [10-20 mg/h]) intra-operatively and for 24 h post-operatively plus GA or GA alone. Post-operative pain at rest and with coughing was significantly less for up to 1 month post-operatively in the TEA + GA group compared to the GA alone group. Furthermore, analgesic use, mechanical ventilation time, ICU stay time, and hospital stay time were reduced in the TEA + GA group compared to the GA alone group.
Read the article summaryNT-proBNP predicts outcome following emergent surgery
As published in the British Journal of Anaesthesia, measurement of N-terminal pro B-type natruiretic peptide (NT-proBNP) pre- and post-operatively predicts outcome in patients > 50 years of age (n=297) undergoing emergent non-cardiac surgery. A pre-operative NT-proBNP > 725 pg/ml was associated with a 4.8-fold RR of non-fatal MI, acute heart failure, or death between surgery and the 3-year post-operative follow up. Similarly, a post-operative NT-proBNP > 1600 pg/ml was associated with a 4.0-fold RR of non-fatal MI, acute heart failure, or death between surgery and the 3-year post-operative follow up. A pre-operative NT-proBNP > 1740 pg/ml was associated with a 6.9 RR for major adverse cardiac events during the post-operative hospital stay.
Read the article summaryIncreased risk of skin cancer in RCC treated with multikinase inhibitors
As published in Dermatologic Surgery, RCC patients (n=69) treated with multikinase inhibitors are at increased risk for squamous cell carcinomas and basal cell carcinomas. After a median treatment of 13.5 months, 13.5% and 6.3% of patients treated with sorafenib and sunitinib developed skin cancer, respectively.
Read the article summaryMost Popular Surgery Articles
Last month's top read Top Articles of 20121 Stapled versus hand-sewn anastomoses in emergency general surgery: A retrospective review of outcomes in a unique patient population The Journal of Trauma and Acute Care Surgery, April 29, 2013 Evidence Based Medicine Review Article
2 Preoperative skin antiseptics for preventing surgical wound infections after clean surgery Cochrane Reviews, April 3, 2013 Review Article
3 Minimal access surgery compared with medical management for gastro-oesophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX) British Medical Journal, April 23, 2013
4 Transgastric appendicectomy British Journal of Surgery, April 15, 2013
5 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
6 Thromboprophylaxis for trauma patients Cochrane Reviews, April 1, 2013 Review Article
7 Topical Treatment with Basic Fibroblast Growth Factor Promotes Wound Healing and Barrier Recovery Induced by Skin Abrasion Skin Pharmacology and Physiology, November 12, 2012
8 Laparoscopic repair for perforated peptic ulcer disease Cochrane Reviews, March 8, 2013 Review Article
9 Mitogen-activated protein kinases regulate vascular reactivity after hemorrhagic shock through myosin light chain phosphorylation pathway The Journal of Trauma and Acute Care Surgery, April 3, 2013
10 Associations of anorectal malformations and related syndromes Pediatric Surgery International, April 19, 2013 Review Article
11 Intraoperative Management and Repair of Bile Duct Injuries Sustained during 10,123 Laparoscopic Cholecystectomies in a High-Volume Referral Center Journal of the American College of Surgeons, March 25, 2013
12 Combined laparoscopic and open extraperitoneal approach to scrotal hernias Hernia, March 26, 2013
13 Mutations in Specific Codons of the KRAS Oncogene are Associated with Variable Resistance to Neoadjuvant Chemoradiation Therapy in Patients with Rectal Adenocarcinoma Annals of Surgical Oncology, March 5, 2013
14 Laparoscopy-assisted gastrectomy following neoadjuvant chemotherapy for advanced gastric cancer - strategies for development Translational Gastrointestinal Cancer, April 17, 2013 Free full text
15 Life after near death: Long-term outcomes of emergency department thoracotomy survivors The Journal of Trauma and Acute Care Surgery, April 29, 2013
16 Advances in Immune Regulation in Transplantation Discovery Medicine, April 1, 2013 Free full text
17 Thoracoscopic thymectomy: technical pearls to a 21st century approach Journal of Thoracic Disease, April 17, 2013
18 DNA Ploidy is an Independent Predictor of Survival in Breast Invasive Ductal Carcinoma: A Long-term Multivariate Analysis of 393 Patients Annals of Surgical Oncology, April 9, 2013
19 Complications Associated With Injectable Soft-Tissue Fillers A 5-Year Retrospective Review Complications With Injectable Soft-Tissue Fillers JAMA Facial Plastic Surgery, March 29, 2013 Review Article
20 Clinical Practice Guidelines for the Perioperative Nutritional, Metabolic, and Nonsurgical Support of the Bariatric Surgery Patient -- 2013 Update: Cosponsored by American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Surgery Endocrine Practice, March 28, 2013 Free full text Clinical Guideline
Indexed Journals in Surgery: Surgery, Journal of the American College of Surgeons, Annals of Surgery more
Other Topics in Surgery
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