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Surgery - Basic Science/Genetics News & Articles
MDLinx Surgery is your ultimate resource for the latest General Surgery and subspecialty surgery news articles published in over 2,000 peer-reviewed medical journals and popular press. Our diligent team of medical editor’s rank sort and summarize Surgery news articles with topics ranging from: Cardiac Surgery, Critical Care, Vascular, Thoracic, Peds Surgery, Neurosurgery and much more. On this page you may also find bonus content that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read “ as well as clinical pearls taken from our Smartest Doc quiz competition.
As an MDLinx member you can stay current in less than 5 minutes a day via newsletters that encompass a list of the top ranked Surgery articles delivered directly to your inbox. As a member you may also receive monthly updates about upcoming Surgery conferences, Category 1 & 2 CME opportunities, Market Research invitations and much more!
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Articles
Latest (1) Full Text Articles (20)821 Lentiviral-mediated Overexpression of Bcl-xL Protects Primary Endothelial Cells From Ischemia/Reperfusion Injury-induced Apoptosis The Journal of Heart and Lung Transplantation, September 17, 2009
822 Association analysis of the PHOX2B gene with Hirschsprung disease in the Han Chinese population of Southeastern China Journal of Pediatric Surgery, September 16, 2009
823 Loss of viability and induction of apoptosis in human keratinocytes exposed to Staphylococcus aureus biofilms in vitro Wound Repair and Regeneration, September 16, 2009
824 Differential expression of cyclooxygenases in hypertrophic scar and keloid tissues Wound Repair and Regeneration, September 16, 2009
825 A new mutation in Muir-Torre syndrome associated with familiar transmission of different gastrointestinal adenocarcinomas European Journal of Surgical Oncology, September 15, 2009
826 Microarray analysis of microRNA expression in renal clear cell carcinoma European Journal of Surgical Oncology, September 15, 2009
827 HER-family gene amplification and expression in resected pancreatic cancer European Journal of Surgical Oncology, September 15, 2009
828 High Mobility Group A: a novel biomarker and therapeutic target in pancreatic adenocarcinoma The Surgeon, September 14, 2009
829 Two-year follow-up of a prospective study of circulating regulatory T cells in renal transplant patients Clinical Transplantation, September 14, 2009
830 Long-term results after conversion from calcineurin inhibitors to sirolimus in renal transplant patients Clinical Transplantation, September 11, 2009
831 KRAS Mutation Correlates With Accelerated Metastatic Progression in Patients With Colorectal Liver Metastases Annals of Surgical Oncology, September 8, 2009
832 Interferon-gamma 874A>T genetic polymorphism is associated with infectious complications following surgery in patients with thoracic esophageal cancer Surgery, September 8, 2009
833 Heat-shock protein 70 gene polymorphism is associated with the severity of diabetic foot ulcer and the outcome of surgical treatment British Journal of Surgery, September 4, 2009
834 Proinflammatory Cytokine Effects on Mesenchymal Stem Cell Therapy for the Ischemic Heart Full Text Annals of Thoracic Surgery, September 4, 2009
835 Biopsy diagnostics in renal allograft rejection: from histomorphology to biological function Transplant International, September 4, 2009
836 Rapamycin-treated mature dendritic cells have a unique cytokine secretion profile and impaired allostimulatory capacity Transplant International, September 4, 2009
837 CXC chemokines play a critical role in liver injury, recovery, and regeneration The American Journal of Surgery, September 3, 2009
838 Impact of the CYP2D6 genotype on post-operative intravenous oxycodone analgesia Acta Anaesthesiologica Scandinavica, September 3, 2009
839 Comparative analysis of thymidylate synthase at the protein, mRNA, and DNA levels as prognostic markers in colorectal adenocarcinoma Journal of Surgical Oncology, September 2, 2009
840 Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway Journal of Surgical Oncology, September 2, 2009
Clinical Pearls in Surgery
- Surgery is the cornerstone of treatment for advanced acne inversa
- Positive botulinum toxin type A response is a significant predictor of migraine surgery success.
- After having bariatric surgery, sleep duration increases significantly
Highlights in Surgery
Epidural anesthesia reduces post-CABG pain
As published in the Journal of Cardiac Surgery, thoracic epidural anesthesia (TEA) plus general anesthesia (GA) is superior to GA alone in managing post-operative CABG pain. Forty patients undergoing elective CABG were randomized to receive TEA (0.25% bipivacaine [10-20 mg/h]) intra-operatively and for 24 h post-operatively plus GA or GA alone. Post-operative pain at rest and with coughing was significantly less for up to 1 month post-operatively in the TEA + GA group compared to the GA alone group. Furthermore, analgesic use, mechanical ventilation time, ICU stay time, and hospital stay time were reduced in the TEA + GA group compared to the GA alone group.
Read the article summaryNT-proBNP predicts outcome following emergent surgery
As published in the British Journal of Anaesthesia, measurement of N-terminal pro B-type natruiretic peptide (NT-proBNP) pre- and post-operatively predicts outcome in patients > 50 years of age (n=297) undergoing emergent non-cardiac surgery. A pre-operative NT-proBNP > 725 pg/ml was associated with a 4.8-fold RR of non-fatal MI, acute heart failure, or death between surgery and the 3-year post-operative follow up. Similarly, a post-operative NT-proBNP > 1600 pg/ml was associated with a 4.0-fold RR of non-fatal MI, acute heart failure, or death between surgery and the 3-year post-operative follow up. A pre-operative NT-proBNP > 1740 pg/ml was associated with a 6.9 RR for major adverse cardiac events during the post-operative hospital stay.
Read the article summaryIncreased risk of skin cancer in RCC treated with multikinase inhibitors
As published in Dermatologic Surgery, RCC patients (n=69) treated with multikinase inhibitors are at increased risk for squamous cell carcinomas and basal cell carcinomas. After a median treatment of 13.5 months, 13.5% and 6.3% of patients treated with sorafenib and sunitinib developed skin cancer, respectively.
Read the article summaryMost Popular Surgery Articles
Last month's top read Top Articles of 20121 Stapled versus hand-sewn anastomoses in emergency general surgery: A retrospective review of outcomes in a unique patient population The Journal of Trauma and Acute Care Surgery, April 29, 2013 Evidence Based Medicine Review Article
2 Preoperative skin antiseptics for preventing surgical wound infections after clean surgery Cochrane Reviews, April 3, 2013 Review Article
3 Minimal access surgery compared with medical management for gastro-oesophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX) British Medical Journal, April 23, 2013
4 Transgastric appendicectomy British Journal of Surgery, April 15, 2013
5 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
6 Thromboprophylaxis for trauma patients Cochrane Reviews, April 1, 2013 Review Article
7 Topical Treatment with Basic Fibroblast Growth Factor Promotes Wound Healing and Barrier Recovery Induced by Skin Abrasion Skin Pharmacology and Physiology, November 12, 2012
8 Laparoscopic repair for perforated peptic ulcer disease Cochrane Reviews, March 8, 2013 Review Article
9 Mitogen-activated protein kinases regulate vascular reactivity after hemorrhagic shock through myosin light chain phosphorylation pathway The Journal of Trauma and Acute Care Surgery, April 3, 2013
10 Associations of anorectal malformations and related syndromes Pediatric Surgery International, April 19, 2013 Review Article
11 Intraoperative Management and Repair of Bile Duct Injuries Sustained during 10,123 Laparoscopic Cholecystectomies in a High-Volume Referral Center Journal of the American College of Surgeons, March 25, 2013
12 Combined laparoscopic and open extraperitoneal approach to scrotal hernias Hernia, March 26, 2013
13 Mutations in Specific Codons of the KRAS Oncogene are Associated with Variable Resistance to Neoadjuvant Chemoradiation Therapy in Patients with Rectal Adenocarcinoma Annals of Surgical Oncology, March 5, 2013
14 Laparoscopy-assisted gastrectomy following neoadjuvant chemotherapy for advanced gastric cancer - strategies for development Translational Gastrointestinal Cancer, April 17, 2013 Free full text
15 Life after near death: Long-term outcomes of emergency department thoracotomy survivors The Journal of Trauma and Acute Care Surgery, April 29, 2013
16 Advances in Immune Regulation in Transplantation Discovery Medicine, April 1, 2013 Free full text
17 Thoracoscopic thymectomy: technical pearls to a 21st century approach Journal of Thoracic Disease, April 17, 2013
18 DNA Ploidy is an Independent Predictor of Survival in Breast Invasive Ductal Carcinoma: A Long-term Multivariate Analysis of 393 Patients Annals of Surgical Oncology, April 9, 2013
19 Complications Associated With Injectable Soft-Tissue Fillers A 5-Year Retrospective Review Complications With Injectable Soft-Tissue Fillers JAMA Facial Plastic Surgery, March 29, 2013 Review Article
20 Clinical Practice Guidelines for the Perioperative Nutritional, Metabolic, and Nonsurgical Support of the Bariatric Surgery Patient -- 2013 Update: Cosponsored by American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Surgery Endocrine Practice, March 28, 2013 Free full text Clinical Guideline
Indexed Journals in Surgery: Surgery, Journal of the American College of Surgeons, Annals of Surgery more
Other Topics in Surgery
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