Cholecystolithiasis after Gastric Bypass: A Clinical, Biochemical, and Ultrasonographic 3-year Follow-up Study
Obesity Surgery, 07/11/2012
Nagem R et al. – There was a high incidence of Cholecystolithiasis (CL) after Roux–en–Y gastric bypass (RYGBP), occurring primarily in the first 2 years postoperatively. There was no identified predictive factor for gallstone formation after RYGBP. Most patients who formed gallstones were symptomatic, some with potentially severe complications.Methods
- A prospective observational study was performed on 40 morbidly obese patients free of gallbladder disease undergoing RYGBP at a public hospital in Brazil between February and October 2007.
- They were followed up clinically, biochemically (lipid profile), and ultrasonographically at 6 months and 1, 2, and 3 years after surgery.
- Postoperative prophylactic bile salt therapy (ursodiol) was not prescribed. Of the 40 patients, 38 completed the 3–year follow–up.
- They were divided into two groups: those who formed gallstones and those who did not.
- These groups were compared with respect to gender, age, preoperative body mass index (BMI) and lipid profile results, and postoperative percentage of excess BMI lost (%EBL) and lipid profile results.
- The overall postoperative incidence of CL was 28.9 % (11 out of 38), with a 15.7 % incidence of symptomatic CL (6 out of 38).
- Gender, age, preoperative BMI, postoperative %EBL, and preoperative and postoperative lipid profile results were not identified as predictive factors for CL after RYGBP.