Smartest Doc
Cerebral and Somatic Near-Infrared Spectroscopy Measurements During Fluid Challenge in Cardiac Surgery Patients: A Descriptive Pilot Study
Journal of Cardiothoracic and Vascular Anesthesia, 06/12/2012
Fellahi JL et al. – Cerebral (rSO2b) and rSO2s cannot be used to provide noninvasive estimation of central venous oxygen saturation (ScvO2), and trends in rSO2b and rSO2s cannot be considered as noninvasive surrogates for the trend in ScvO2 after cardiac surgery. Different independent variables contribute to the prediction of ScvO2, rSO2b, and rSO2s.
Methods- Fifty consecutive adult patients.
- Admission to the intensive care unit after cardiac surgery and investigation before and after a fluid challenge.
- Simultaneous comparative ScvO2, rSO2b, and rSO2s data points were collected from a blood–gas analyzer and the EQUANOX monitor (Nonin Medical, Inc, Plymouth, MN).
- Correlations were determined by linear regression.
- Multiple stepwise linear regression models were used to assess independent variables associated with changes in ScvO2, rSO2b, and rSO2s.
- A statistically significant relationship was found between absolute values of ScvO2 and rSO2b (r=0.42, p<0.001) but not between absolute values of ScvO2 and rSO2s (r=0.18, p=0.066).
- No relationship was found between percent changes in ScvO2 and rSO2b (r=0.05, p=0.715) and between percent changes in ScvO2 and rSO2s (r=0.02, p=0.886) after the fluid challenge.
- Cardiac index contributed to the prediction of changes in ScvO2 (regression coefficient=–4.09, p=0.006), whereas the mean arterial pressure contributed to the prediction of changes in rSO2b (regression coefficient=–0.05, p=0.027).
