Invasive fungal infections following liver transplantation 2003-2007: Incidence, risk factors, survival and the impact of fluconazole-resistant Candida parapsilosis
Liver Transplantation, 05/16/2012
Raghuram A et al. – In particular, identification of pre–transplant fungal “colonization” may offer an opportunity to modify risk prior to or at the time of transplantation. Insufficient dosing of fluconazole prophylaxis may adversely affect incidence of invasive fungal infections (IFI) and patient outcomes by promoting resistant Candida strains. Furthermore, liver transplant numbers and prophylactic strategies may contribute to institutional outbreaks of resistant Candida strains.