Assessment of the Interface Between Retroperitoneal Fat Infiltration of Pancreatic Ductal Carcinoma and the Major Artery by Multidetector-Row Computed Tomography: Surgical Outcomes and Correlation with Histopathological Extension
World Journal of Surgery,  Clinical Article

Yamamoto Y et al. – The grading criteria for retroperitoneal fat infiltration may be useful as a predictor of survival after pancreaticoduodenectomy for pancreatic head carcinoma. Pancreaticoduodenectomy with portal vein resection could provide favorable survival in patients with grade 1 retroperitoneal fat infiltration, even if histopathological portal vein invasion is present.

Methods
  • The clinical records of 132 patients who underwent macroscopic curative pancreaticoduodenectomy for invasive ductal carcinoma of the pancreas between 2004 and 2008 were retrospectively examined.
  • The clinicopathological factors, including retroperitoneal fat infiltration classified into four groups by multidetector–row computed tomography (MDCT), were analyzed.
  • The relationship between the grade of retroperitoneal fat infiltration and surgical outcomes, as well as various histopathological factors, was also investigated.

Results
  • The 5 year survival rate was 55.6 % for grade 0 infiltration (n = 8), 38.7 % for grade 1 (n = 54), 16.4 % for grade 2 (n = 49), and 0 % for grade 3 (n = 21).
  • There were significant differences in survival in each group.
  • Extrapancreatic nerve invasion and the surgical margin status were significantly associated with retroperitoneal fat infiltration demonstrated on MDCT.
  • According to the grading classification among the 43 patients with pathological portal vein invasion, the 5 year survival rate was 45.9 % for patients with grade 1, which was significantly better survival that those with grade 2 (P = 0.007).

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Surgery

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Surgery Articles

1 Band removal and conversion to sleeve or bypass: are they equally safe? Surgical Endoscopy, June 4, 2014    Clinical Article

2 Accurate prediction of anastomotic leakage after colorectal surgery using plasma markers for intestinal damage and inflammation Journal of the American College of Surgeons, June 27, 2014    Clinical Article

3 Lift-and-fill face lift: Integrating the fat compartments Plastic and Reconstructive Surgery, June 5, 2014    Clinical Article

4 A randomized, controlled, crossover study of sacral nerve stimulation for irritable bowel syndrome Annals of Surgery, June 9, 2014    Evidence Based Medicine    Clinical Article

5 A meta-analysis of 2-year effect after surgery: Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity and diabetes mellitus Obesity Surgery, June 17, 2014    Evidence Based Medicine    Review Article

6 Percutaneous transesophageal gastro-tubing for management of gastric leakage after sleeve gastrectomy Obesity Surgery, June 16, 2014    Clinical Article

7 A novel approach to abdominoplasty: TULUA modifications (Transverse Plication, No Undermining, Full Liposuction, Neoumbilicoplasty, and Low Transverse Abdominal Scar) Aesthetic Plastic Surgery, May 5, 2014    Clinical Article

8 Chimeric autologous costal cartilage graft to prevent warping Plastic and Reconstructive Surgery, June 6, 2014    Clinical Article

9 Single-stage versus 2-stage sleeve gastrectomy as a conversion after failed adjustable gastric banding: 30-day outcomes Surgical Endoscopy, June 11, 2014    Review Article

10 Laparoscopic sleeve gastrectomy using 42-French versus 32-French bougie: The first-year outcome Obesity Surgery, March 3, 2014    Clinical Article

11 Breast conservation: Is the survival better for mastectomy? Journal of Surgical Oncology, June 4, 2014    Review Article

12 An initial experience with 85 consecutive robotic-assisted rectal dissections: improved operating times and lower costs with experience Surgical Endoscopy, June 18, 2014    Review Article

13 Upper gastrointestinal series after Roux-en-Y gastric bypass for morbid obesity: effectiveness in leakage detection. A systematic review of the literature Obesity Surgery, May 13, 2014    Review Article

14 Predictors of weight loss at 1 year after laparoscopic adjustable gastric banding and the role of presurgical quality of life Obesity Surgery, June 2, 2014    Clinical Article

15 Outcome analysis of single incision vs traditional multiport sleeve gastrectomy: A matched cohort study Obesity Surgery, June 23, 2014    Clinical Article

16 High incidence of trocar site hernia after laparoscopic or robotic Roux-en-Y gastric bypass Surgical Endoscopy, May 8, 2014    Clinical Article

17 Long-term effects of laparoscopic Roux-en-Y gastric bypass on diabetes mellitus, hypertension and dyslipidaemia in morbidly obese patients Obesity Surgery, June 26, 2014    Clinical Article

18 Short-term surgical outcomes from a randomized controlled trial to evaluate laparoscopic and open D3 dissection for stage II/III colon cancer: Japan clinical oncology group study JCOG 0404 Annals of Surgery, June 10, 2014    Evidence Based Medicine    Clinical Article

19 Greater weight loss with the omega loop bypass compared to the Roux-en-Y gastric bypass: a comparative study Obesity Surgery, May 19, 2014    Clinical Article

20 Risk factors for 30-day readmissions and modifiying postoperative care after gastric bypass surgery Journal of the American College of Surgeons, June 3, 2014    Review Article

Indexed Journals in Surgery: Surgery, Journal of the American College of Surgeons, Annals of Surgerymore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close