Liver Resection for Multiple Colorectal Liver Metastases with Surgery Up-front Approach: Bi-institutional Analysis of 736 Consecutive Cases
World Journal of Surgery,

Saiura A et al. – In patients with multiple liver metastases, the number of liver metastases has less impact on the prognosis than other prognostic factors. Complete resection with repeat metastasectomy offers a chance of cure even in patients with numerous colorectal liver metastases (i.e., those with eight or more nodules).

Methods
  • Data collected prospectively over a 16–year period for 736 patients who underwent hepatic resection at two different centers were reviewed.
  • Patients were divided into three groups depending on the number of tumors as follows: group A, between one and three tumors (n = 493); group B, between four and seven tumors (n = 141); and group C, eight or more tumors (n = 102).

Results
  • The 5–year overall and recurrence–free survival rates were 51 and 21 %, respectively, for the entire patient cohort, 56 and 29 % in group A, 41 and 12 % in group B, and 33 and 1.7 % in group C.
  • Multivariate analysis showed that decreased survival was associated with positive lymph node metastasis of the primary tumor, the presence of extrahepatic tumors, a maximum liver tumor size >5 cm, and tumor exposure during liver resection.

Please login or register to follow this author.
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Surgery

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Surgery Articles

1 A novel endoscopic weight loss therapy using gastric aspiration: results after 6 months Endoscopy, October 7, 2014    Clinical Article

2 Abdominoplasty and seroma - A prospective randomised study comparing scalpel and handheld electrocautery dissection Journal of Plastic, Reconstructive & Aesthetic Surgery, October 29, 2014    Clinical Article

3 Four-step medial thighplasty: refined and reproducible Plastic and Reconstructive Surgery, November 6, 2014    Clinical Article

4 Non-invasive fat reduction of the flanks using a new cryolipolysis applicator and overlapping, two-cycle treatments Lasers in Surgery and Medicine, November 24, 2014    Clinical Article

5 Elective resection versus observation after nonoperative management of complicated diverticulitis with abscess: A systematic review and meta-analysis Diseases of the Colon and Rectum, November 14, 2014    Evidence Based Medicine    Review Article

6 Laparoscopic revolution in bariatric surgery Full Text World Journal of Gastroenterology, November 10, 2014    Free full text    Clinical Article

7 Effect of vagotomy during Roux-en-Y gastric bypass surgery on weight loss outcomes Obesity Research & Clinical Practice, November 4, 2014    Clinical Article

8 Comparison of stricture rates using three different gastrojejunostomy anastomotic techniques in laparoscopic Roux-en-Y gastric bypass Surgical Endoscopy, November 5, 2014    Review Article

9 Colorectal stenting: An advanced approach to malignant colorectal obstruction Full Text World Journal of Gastroenterology, November 25, 2014    Free full text    Review Article

10 The effect of the endoscopic duodenal-jejunal bypass liner on obesity and type 2 diabetes mellitus, a multicenter randomized controlled trial Annals of Surgery, November 19, 2014    Clinical Article

11 Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass: A single center experience with 2 years follow-up Obesity Surgery, August 8, 2014    Clinical Article

12 Hartmanns procedure vs loop colostomy in the treatment of obstructive rectosigmoid cancer Full Text World Journal of Emergency Surgery, October 21, 2014    Free full text    Clinical Article

13 Comparative effectiveness of laparoscopic adjustable gastric banding vs laparoscopic gastric bypass JAMA Surgery, November 3, 2014    Clinical Article

14 Fenestrated endovascular aortic aneurysm repair (FEVAR) procedure implemented at Danbury Hospital Western Connecticut Health Network, November 12, 2014

15 Endoscopic sleeve gastroplasty for the treatment of obesity Endoscopy, November 17, 2014    Clinical Article

16 Chemicals found in everyday fruits could minimise organ damage after heart attack and stroke University of Cambridge News, November 14, 2014

17 Aesthetic refinements in body contouring in the massive weight loss patient: Part 2. Arms Plastic and Reconstructive Surgery, November 7, 2014    Clinical Article

18 Study finds gallbladder surgery can wait Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center News, October 6, 2014

19 Initial experience with endoscopic sleeve gastroplasty: technical success and reproducibility in the bariatric population Endoscopy, November 13, 2014    Clinical Article

20 Does volume of cardiac catheterizations correlate with better outcomes? The Children's Hospital of Philadelphia, November 19, 2014

Indexed Journals in Surgery: Surgery, Journal of the American College of Surgeons, Annals of Surgerymore