Sentinel lymph node biopsy predicts lymph node metastasis in early gastric cancer: a retrospective analysis
Digestive Surgery, 05/03/2012Dong LF et al.
Sentinel lymph node (SLN)–guided minimally invasive surgery could be safely performed in early gastric cancer (EGC) according to feasible criteria.
A solitary metastasis lymph node was taken as SLN, the features of lymph node metastasis were analyzed retrospectively in 255 patients with EGC, and the result was then compared with a SLN biopsy in 23 patients with EGC.
Depth of invasion and tumor size were independent risk factors for lymph node metastasis in EGC.
The lymph node metastasis rate for mucosal carcinoma with a diameter <4 cm was 2.5%, and it was 13.3% when the diameter was ≥4 cm (p = 0.040).
For submucosal carcinoma, it was 25.4% when the tumor diameter was <3 cm and 50.5% when the diameter was ≥3 cm (p = 0.003).
The accuracy, sensitivity, and specificity of SLN biopsy in EGC was 100%, respectively.
The distribution characteristics of SLN were consistent with those of lymph node metastasis in EGC.
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