SLEEVEPASS: A randomized prospective multicenter study comparing laparoscopic sleeve gastrectomy and gastric bypass in the treatment of morbid obesity: preliminary results
Surgical Endoscopy, 04/09/2012
Helmio M et al. – At 30–day analysis SG is associated with a shorter operating time and fewer early minor complications compared to RYGB. There were no significant differences in major complications or early reoperations. Long–term follow–up is required to determine the effect on weight loss, resolution of obesity–related comorbidities, and improvement of quality of life.Methods
- A total of 240 morbidly obese (BMI = 35–66 kg/m²) patients evaluated by a multidisciplinary team were randomized to undergo either RYGB or SG.
- There were 117 patients in the RYGB group and 121 in the SG group; two patients had to be excluded after randomization.
- Both study groups were comparable regarding age, gender, BMI, and comorbidities.
- There was no 30–day mortality.
- The median operating time was significantly shorter in the SG group (66 min vs. 94 min, p < 0.001).
- All complications were recorded thoroughly.
- There were 7 (5.8 %) major complications following SG and 11 (9.4 %) after RYGB (p = 0.292).
- Nine (7.4 %) SG patients and 20 (17.1 %) RYGB patients had minor complications (p = 0.023).
- The overall morbidity was 13.2 % after SG and 26.5 % after RYGB (p = 0.010).
- There were three (2.5 %) early reoperations after SG and four (3.3 %) after RYGB (p = 0.719).