Population pharmacokinetics of prophylactic cefoxitin in patients undergoing colorectal surgery
European Journal of Clinical Pharmacology, 02/03/2012
Clinical Article
Isla A et al. – To ensure cefoxitin target concentrations during surgery, authors recommend that cefoxitin be administered every 1.5 h in patients with a CLCR ≥60 mL/min and every hour if the CLCR is ≥100 mL/min. Administration by continuous infusion preceded by a bolus injection should also be considered.






