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Predictive factors of excess body weight loss 1 year after laparoscopic bariatric surgery
Surgical Endoscopy, 01/17/2012
Ortega E et al. – The data indicate that some of the characteristics that would have subjects referred early for BS were associated with higher weight loss. Therefore, the timing of laparoscopic bariatric surgery (BS) might be an important factor for morbid obesity (MO) individuals in which medical weight loss intervention has failed.
Methods- This retrospective study included 407 subjects (F/M 3:1, median age = 44 years) who underwent laparoscopic Roux–en–Y gastric bypass (RYGB, n = 307) or sleeve gastrectomy (SG, n = 100) at the University Hospital and were evaluated 1 year after surgery.
- Baseline median (min–max) body mass index (BMI) was 47 kg/m2 (range = 36–71).
- BMI was higher in the SG than in the RYGB group (53 vs. 46 kg/m2, p < 0.0001).
- Simple correlation analysis showed negative associations between EWL and age, BMI, waist circumference (WC), fasting glucose, HbA1c, triglycerides (TG), blood pressure, and total cholesterol (all p < 0.01).
- EWL (mean ± SD) did not differ by gender (p = 0.2), was lower in diabetic than in nondiabetic subjects (71 ± 17% vs. 79 ± 17%, p < 0.0001), and higher in the RYGB vs. SG group (76 ± 18% vs. 68 ± 15%, p < 0.0001).
- However, SG vs. RYGB differences in EWL disappeared (p = 0.4) after taking into account baseline BMI.
- Multiple regression and logistic analysis showed that younger individuals with lower BMI but higher WC, and lower HbA1c and TG, had higher EWL and a higher rate of successful (EWL ≥ 60%) weight loss.
