Comparative Analysis of Five-Year Survival Results of Laparoscopy-Assisted Gastrectomy versus Open Gastrectomy for Advanced Gastric Cancer: A Case-Control Study Using a Propensity Score Method

Digestive Surgery, 06/01/2012

LAG for AGC might be considered to be a minimally invasive surgery in some selected cases, although a well–designed prospective study comparing LAG with OG for AGC is needed.


  • The authors retrospectively analyzed 89 patients who underwent LAG and 345 patients who underwent OG for AGC between August 1999 and June 2007.
  • A total of 176 matched cases were included in the final analysis.


  • Except for tumor size and reconstruction, there were no statistically significant differences in the clinicopathological parameters between the two groups.
  • Although operation time was significantly longer for LAG than OG (228.3 vs. 183.6 min, p < 0.0001), first flatus time and postoperative hospital stay without complications were significantly shorter in the LAG group (3.2 vs. 3.7 days, p < 0.0001; 7.0 vs. 10.4 days, p < 0.0001, respectively).
  • Operation–related complications occurred in 7 cases (8.0%) in both groups. 13 patients (14.8%) in the LAG group and 15 patients (17.1%) in the OG group had recurrence.
  • There was no statistically significant difference in the 5–year and disease–free survival rates between LAG and OG.

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