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Anti-cyclic citrullinated peptide antibodies as a discriminating marker between rheumatoid arthritis and chronic hepatitis C-related polyarthropathy
Rheumatology International, 11/05/09
Ezzat WM et al. –Anti-CCP antibodies are reliable laboratory markers to differentiate between RA and HCV-related polyarthropathy.
Methods- Anti-cyclic citrullinated peptide (CCP) antibodies and RF determined in sera of 30 patients with RA and 22 patients with HCV-related polyarthropathy
- Anti-CCP antibodies positive in 83.3% of patients with RA and 4.5% in patients with HCV and polyarthropathy
- RF positive in 90% of RA patients and 81.1% of HCV patients with polyarthropathy
- Anti-CCP antibodies showed higher specificity for RA compared with RF (95.4 vs. 18.2%)
- Sensitivity of anti-CCP comparable to that of RF (83.3 vs. 90%)
Today in Basic Science/Genetics...keeping you current
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Lipid peroxidation, glutathione, vitamin E, and antioxidant enzymes in synovial fluid from patients with osteoarthritis
International Journal of Rheumatic Diseases, 11/23/09
Low plasma levels of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNF &alpha), and vascular endothelial growth factor (VEGF) in patients with alpha1-antitrypsin deficiency-related fibromyalgia
Clinical Rheumatology, 11/23/09
Circulating microparticles remain associated with complement activation despite intensive anti-inflammatory therapy in early rheumatoid arthritis
Annals of Rheumatic Diseases, 11/23/09
Today in Rheumatoid Arthritis...keeping you current
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A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
Canadian Medical Association Journal, 11/23/09
Circulating microparticles remain associated with complement activation despite intensive anti-inflammatory therapy in early rheumatoid arthritis
Annals of Rheumatic Diseases, 11/23/09
Immunocytokines: the long-awaited therapeutic magic bullet in rheumatoid arthritis
Arthritis Research & Therapy, 11/23/09
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