Rheumatology Medical News about fibroblast growth factor

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Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation of Elk-1 in human adult articular chondrocytes
Open Access Rheumatology: Research and Reviews, 11/03/09

Im H–J et al. – The results suggest that sumoylation antagonizes the phosphorylation–dependent transactivation capacity of Elk–1. This attenuates transcription of its downstream target gene MMP–13 to maintain the integrity of cartilage ECM homeostasis.

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The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1 alpha in human rheumatoid arthritis fibroblast-like synoviocyte
Rheumatology International, 10/30/09 Relevance Score: 81%

Platelet gel for treatment of mucocutaneous lesions related to graft-versus-host disease after allogeneic hematopoietic stem cell transplant
Transfusion, 10/13/09 Relevance Score: 81%

Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts
Arthritis & Rheumatism, 11/11/09 Relevance Score: 80%

Oxidative Stress, Diabetes, and Diabetic Complications
Hemoglobin, 10/23/09 Relevance Score: 80%

Therapeutic Angiogenesis by Controlled-Release Fibroblast Growth Factor in a Patient With Churg-Strauss Syndrome Complicated by an Intractable Ischemic Leg Ulcer
The American Journal of the Medical Sciences, 10/20/09 Relevance Score: 80%