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Pathogenic role of anti-endothelial cell antibodies in autoimmune rheumatic diseases
Lupus, 11/10/09
Domiciano DS et al. – Anti–endothelial cells antibodies have been detected in numerous autoimmune and inflammatory diseases, including systemic lupus erythematous, rheumatoid arthritis, vasculitis and sarcoidosis. Anti–endothelial cells antibodies bind to endothelial cell antigens and induce endothelial damage. Their effects on the endothelial cell have been considered responsible, at least in part, by the vascular injury which occurs in these pathological conditions.
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Comparison of autoinflammation and autoimmunity using TRAPS and rheumatoid arthritis as prototypes of these conditions
International Journal of Clinical Rheumatology, 12/04/09
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