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Cross-talk of the environment with the host genome and the immune system through endogenous retroviruses in systemic lupus erythematosus
Lupus, 11/04/09
Blank M et al. – Environmental factors are capable of triggering the expression of human endogenous retroviruses and induce an autoimmune response. Infection can promote the expression of human endogenous retroviruses by molecular mimicry or by functional mimicry. In the current review the authors summarize the current knowledge on infections, molecular mimicry, cross–reactivity and epigenetics contribution for trigger human endogenous retroviruses expression and pathogenesis in lupus patients.
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Today in Autoimmune/Heritable...keeping you current
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Levels of plasmacytoid dendritic cells and type-2 myeloid dendritic cells are reduced in peripheral blood of patients with primary Sjogrens syndrome
Annals of Rheumatic Diseases, 11/23/09
Genetic background of systemic sclerosis: autoimmune genes take centre stage
Rheumatology, 11/23/09
Identification of anti-prothrombin antibodies in the anti-phospholipid syndrome that display the prothrombinase activity
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Today in Systemic Lupus (SLE)...keeping you current
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Influence of race/ethnicity on response to lupus nephritis treatment: The ALMS study
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Analysis of correlations between selected endothelial cell activation markers, disease activity, and nailfold capillaroscopy microvascular changes in SLE patients
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