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See Latest ArticlesIncidence and predictors of osteonecrosis among cyclosporin- or tacrolimus-treated renal allograft recipients
Rheumatology International, 11/04/09
Takao M et al. – There was a lower incidence of osteonecrosis of the hip and knee in renal allograft recipients treated with cyclosporin or tacrolimus. In the patients treated with improved immunosuppressive regimens, delayed graft function was a significant early predictor of osteonecrosis.
Methods- The subjects were 232 renal allograft recipients who had MRI for osteonecrosis of the hip and knee 3 months or longer after transplant
- Evidence of osteonecrosis was visible on the MRI of 11 recipients (4.7%, 95% confidence interval 2.4–8.3)
- Univariate and multivariate logistic regression analyses indicated that delayed graft function was the most important predictor of osteonecrosis
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Effect of alendronate on bone metabolic indices and bone mineral density in patients treated with high-dose glucocorticoid: A prospective study
Osteoporosis International, 11/25/09
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