Your Messages Inbox (38) 
Your Unread Messages
See All
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Rapid correction of low vitamin D status in nursing home residents 3. 2008 Exclusive Survey—Earnings: Good news for primary care income 4. Medicare pay-for-reporting effort draws fire from frustrated doctors 5. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment
Top Ten Searches
rheumatoid arthritis lupus polymyalgia sjogrens fibromyalgia amyloidosis vasculitis urate raynauds myositisYour Article Summary
Empirical evaluation of the inter-relationship of articular elements involved in the pathoanatomy of knee osteoarthritis using Magnetic Resonance Imaging
BMC Musculoskeletal Disorders, 11/06/09
Meredith DS et al. – These results support an inter-relationship of multiple articular elements in the pathoanatomy of knee OA.
Methods- Cross-sectional study
- Knee MRI scans from patients over 45 years old assessed using semi-quantitative knee MRI assessment form
- Form included 6 distinct elements: cartilage, bone marrow lesions, osteophytes, subchondral sclerosis, joint effusion and synovitis
- Each type of pathology graded using ordinal scale with value of zero indicating no pathology and higher values indicating increasingly severe levels of pathology
- Principal dependent variable for comparison was mean cartilage disease score (CDS), which captured aggregate extent of involvement of articular cartilage
- Distribution of CDS compared to individual and cumulative distributions of each articular element using Chi-squared test
- Correlations between pathological change in various articular structures were assessed in Spearman correlation table
- Data from 140 patients were available for review
- Cohort had median age of 61 years (range 45-89)
- 61% female
- Cohort included wide spectrum of OA severity
- Our analysis showed statistically significant trend towards pathological change involving more articular elements as CDS worsened
- Comparison of CDS to change in severity of pathology of individual articular elements showed statistically significant trends towards more severe pathology as CDS worsened for osteophytes , bone marrow lesions , and subchondral sclerosis , but not joint effusion or synovitis
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Hepatoprotective effect of TNF-alpha blockade in psoriatic arthritis: A cross-sectional study
Annals of Rheumatic Diseases, 11/09/09
Musculoskeletal manifestations in patients with malignant disease
Clinical Rheumatology, 11/13/09
The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid arthritis: A prospective study
Arthritis & Rheumatism, 11/04/09
Today in Diagnostics/Radiology...keeping you current
Receive free subspecialty "5-minute updates" via email
Bisphosphonate therapy: When not to monitor BMD
The Journal of Family Practice, 11/02/09
Medical decision making in patients with knee pain, meniscal tear, and osteoarthritis
Arthritis Care and Research , 11/04/09
Evaluation of occipitocervical subluxation in rheumatoid arthritis patients, using coronal-view reconstructive computed tomography
Spine, 11/17/09
Today in Osteoarthritis...keeping you current
Receive free subspecialty "5-minute updates" via email
Doxycycline for osteoarthritis of the knee or hip
Cochrane Reviews, 10/23/09
Osteoarthritis: A review of treatment options
Geriatrics, 10/21/09
Effect of biomagnetic therapy versus physiotherapy for treatment of knee osteoarthritis: A randomized controlled trial
Journal of Rehabilitation Medicine, 11/20/09
Sponsor
Article Search
Sponsor