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Fuller-Thomson E et al. – Research suggests a role of early-life trauma in the development of arthritis. This study investigated the relationship between childhood physical abuse and osteoarthritis (OA) while controlling for age, sex, race, and socioeconomic status (SES), in addition to the following types of risk factors for OA: 1) concurrent childhood stressors, 2) adult health behaviors, and 3) depression. The association between childhood physical abuse and OA remained significant, even after controlling for many risk factors that may mediate the relationship.

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