Rheumatology Medical News about Men Pain Insulin-Like Growth Factor I

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Perturbed Insulin-like Growth Factor-1 (IGF-1) and IGF Binding Protein-3 Are Not Associated with Chronic Widespread Pain in Men: Results from the European Male Ageing Study
Journal of Rheumatology, 10/16/09

McBeth J et al. – Overall chronic widespread pain (CWP) was not associated with perturbations in IGF–1 and IGFBP–3 concentrations. Hypofunctioning of the axis was noted among subjects who were obese and this was not specific to CWP. These data suggest that IGF–1 is unlikely to be etiologically important in relation to CWP, although the relationship with growth hormone remains to be elucidated.

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Insulin-like growth factor-I and its binding proteins 3 and 1 are differentially associated with metabolic syndrome in older men
European Journal of Endocrinology, 11/17/09 Relevance Score: 93%

Serum Insulin-Like Growth Factor-I Concentration Is Associated with Leukocyte Telomere Length in a Population-Based Cohort of Elderly Men
Journal of Clinical Endocrinology and Metabolism, 10/29/09 Relevance Score: 93%

Partial Primary Deficiency of Insulin-Like Growth Factor (IGF)-I Activity Associated with IGF1 Mutation Demonstrates Its Critical Role in Growth and Brain Development
Journal of Clinical Endocrinology and Metabolism, 10/12/09 Relevance Score: 89%

Abbott to Acquire Novel Investigational Biologic to Treat Chronic Pain
Abbott, 11/16/09 Relevance Score: 88%

The Role of Insulin-Like Growth Factor (IGF) Binding Protein-2 in the Insulin-Mediated Decrease in IGF-I Bioactivity
Journal of Clinical Endocrinology and Metabolism, 11/06/09 Relevance Score: 88%