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See Latest ArticlesMedical care costs of patients with rheumatoid arthritis during the prebiologics period in Japan: a large prospective observational cohort study
Modern Rheumatology, 10/15/09
Tanaka E et al. – Outpatient costs for patients with RA increased year after year over the 4-year period under observation. Medical costs were higher with increasing RA disease activity and disability levels.
Methods- 6,771 RA patients (17,666 patient years) enrolled in observational cohort study
- Outpatient costs calculated from billing records dated from 2000 to 2004
- Associations between outpatient costs and variables such as age, RA duration, RA disease activities, and disability levels assessed
- Average outpatient cost gradually increased (+7.7% in 4 years) from 271,498 JPY per year in 2000 to 292,417 JPY per year in 2004
- Medications accounted for approximately 50% of total outpatient costs
- Medication costs increased 29.6% during over 4 years
- Costs increased in association with aging, longer RA duration, higher Disease Activity Score of 28 Joints (DAS28), and higher Japanese version of Health Assessment Questionnaire (J-HAQ) score
- Generalized linear regression analysis revealed that both DAS28 and J-HAQ scores were most significant factors associated with outpatient costs
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Comparison of autoinflammation and autoimmunity using TRAPS and rheumatoid arthritis as prototypes of these conditions
International Journal of Clinical Rheumatology, 12/04/09
CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production
Arthritis Research & Therapy, 11/25/09
No evidence for association of the KLF12 gene with RA in a large UK cohort of >7,000 samples.
Annals of Rheumatic Diseases, 11/23/09
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