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See Latest ArticlesCorrelation of ESR, C3, C4, anti-DNA and lupus activity based on British Isles Lupus Assessment Group Index in patients of rheumatology clinic
Rheumatology International, 10/09/09
Nasiri AS et al. – This study aimed to determine the correlation between of ESR, C3, C4, anti-DNA, and lupus activity and also the construct and criterion validity of the British Isles Lupus Assessment Group (BILAG) index for assessing disease activity in systemic lupus erythematosus (SLE).The findings show that the ESR, C3, C4, and anti-DNA should be used in the evaluation and management of patients with SLE. Also the results show that the BILAG index has construct validity.
Methods- Patients with SLE recruited into cross-sectional study
- Data analyzed for estimating of SLE disease activity [scores on the BILAG index and Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K)]
- Overall BILAG scores determined by highest score achieved in any of the individual systems in respective index
- ESR, C3 levels, C4 levels, anti-dsDNA levels, and SLEDAI-2K scores used in analysis of construct validity
- Statistical analyses performed using ordinal logistic regression for construct validity
- Of 100 patients with SLE, 90% women. Their mean ± SD age was 31.1 ± 9.8 years
- Increasing overall scores on the BILAG index associated with increasing ESRs, decreasing C3 levels, decreasing C4 levels, elevated anti-dsDNA levels, and increasing SLEDAI-2K scores
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Mycophenolate mofetil and intravenous cyclophosphamide are similar as induction therapy for class V lupus nephritis
Kidney International, 11/05/09
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus. A randomized controlled trial
Annals of Rheumatic Diseases, 11/10/09
Influence of race/ethnicity on response to lupus nephritis treatment: The ALMS study
Rheumatology, 11/24/09
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