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IgG4 Related Sclerosing Disease With Multiple Organ Involvements and Response to Corticosteroid Treatment
Journal of Clinical Rheumatology (JCR), 10/14/09
Dhobale S et al. – Great attention has been drawn toward the recently defined IgG4 related sclerosing disease, an entity incorporating autoimmune pancreatitis and other organ involvements, hypergammaglobulinemia and deposition of IgG4 in affected tissues. Corticosteroid treatment of 2 months showed complete resolution of the disease process. The authors demonstrate deposition of C4d in the IgG4 related tubulointerstitial nephritis for the first time.
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