Rheumatology Medical News about spinal disc degeneration

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Association of HTRA1 promoter polymorphism with spinal disc degeneration in Japanese women
Journal of Bone and Mineral Metabolism, 10/19/09

Urano T et al. – HTRA1 (high–temperature requirement A1) has been implicated in the modulation of various disease pathologies. HTRA1 expression is upregulated in osteoarthritic joints, suggesting that it may contribute to the development of this debilitating disease. A genetic variation at the HTRA1 gene promoter locus is associated with spinal disc degeneration, suggesting an involvement of the HTRA1 gene in osteoarthritis.

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Dynamic Bulging of Intervertebral Discs in the Degenerative Lumbar Spine
Spine, 10/30/09 Relevance Score: 83%

Cervical Segmental Motion at Levels Adjacent to Disc Herniation as Determined With Kinetic Magnetic Resonance Imaging
Spine, 10/16/09 Relevance Score: 82%

Lumbar Segmental Mobility According to the Grade of the Disc, the Facet Joint, the Muscle, and the Ligament Pathology by Using Kinetic Magnetic Resonance Imaging
Spine, 11/02/09 Relevance Score: 81%

Gene expression profiles of disc tissues and peripheral blood mononuclear cells from patients with degenerative discs
Journal of Bone and Mineral Metabolism, 10/19/09 Relevance Score: 81%

Percutaneous posterior-lateral lumbar interbody fusion for degenerative disc disease using a B-Twin expandable spinal spacer
European Spine Journal, 10/06/09 Relevance Score: 80%