Rheumatology Medical News about Raloxifene

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Raloxifene: its ossification-promoting effect on female mesenchymal stem cells
Journal of Orthopaedic Science, 10/08/09

Matsumori H et al. – 10–6 M Raloxifene had no ossification–inducing effect on female MSCs, but it had an ossification–promoting effect; it had no osteogenic effect on male MSCs. Therefore, raloxifene has a sex difference with regard to its osteogenic effect on MSCs. Moreover, combined treatment with raloxifene plus OS has an effect on female MSCs. These results provide a useful insight into the possible influence of raloxifene after MSC transplantation in clinical practice.

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Raloxifene and body composition and muscle strength in postmenopausal women: A randomized, double-blind, placebo-controlled trial
European Journal of Endocrinology, 11/05/09 Relevance Score: 88%

Systematic Review: Comparative Effectiveness of Medications to Reduce Risk for Primary Breast Cancer
Annals of Internal Medicine, 11/17/09 Relevance Score: 87%

Benefits and risks of raloxifene by vertebral fracture status
Current Medical Research and Opinion, 11/13/09 Relevance Score: 87%

Effects of raloxifene on the renin–angiotensin–aldosterone system and blood pressure in hypertensive and normotensive osteoporotic postmenopausal women
Geriatrics and Gerontology International, 10/12/09 Relevance Score: 87%

Effects of arzoxifene on bone, lipid markers, and safety parameters in postmenopausal women with low bone mass
Osteoporosis International, 10/06/09 Relevance Score: 85%