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Hudson M et al. – Work disability is prevalent, occurs early, and is associated with markers of disease severity and functional status.

Methods

Cross-sectional, multicenter study
Patients assessed with detailed clinical histories, medical examinations, and self-administered questionnaires
Primary outcome was self-reported work disability
Multiple logistic regression used to assess relationship between selected demographic and clinical variables and work disability

Results

Of 643 patients available for study, 133 (21%) reported work disablity
Work disability in SSc common, even in people with short disease duration, and increased steadily with increasing disease duration
Participants ≤ 65 years and who reported being either disabled or working, 28.0% and 44.8% of patients with disease duration of < 2 and 10–15 years, respectively, reported work-disablity
Significant correlates of work disability included comorbidities, disease duration, diffuse disease, disease severity, pain, fatigue, and physical function

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