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Hepper CT et al. – Following an electronic search of multiple databases and a review of reference lists from various articles, the authors found 6 trials in 5 papers that compared corticosteroid versus placebo and four papers that compared different corticosteroids. Results of corticosteroid compared with placebo showed both a statistically and clinically significant reduction in pain at 1 week, with an average difference between groups of 22%. 2 of 4 trials showed triamcinolone to be more effective in pain reduction than other corticosteroids. The authors concluded that intra–articular corticosteroids reduce knee pain for at least 1 week and that intra–articular corticosteroid injection is a short–term treatment of a chronic problem.

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