Rheumatology

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The prevalence of psoriatic arthritis in people with psoriasis
Arthritis Care and Research , 10/01/09

Ibrahim G et al. – The estimated prevalence of PsA in this population, using the CASPAR criteria, was 13.8%. Misclassification of psoriasis and arthritis, and response bias, indicate that this is probably an overestimate.

• People with psoriasis identified from computerized morbidity indices of 2 large UK general practices
• Total population 22,500
• Questionnaires mailed to all 633 patients thus identified
• 50% sample assessed clinically and proportion had blood samples and radiographs taken
• Patients labeled as having psoriasis cross-referenced with local secondary care morbidity index for PsA and RA
• Figures for prevalence of PsA estimated from these data

• 168 questionnaires returned (response rate 27%) and 93 people (55% of questionnaire respondents) examined
• Of these 93 people, 12 (4 of whom were cross-referenced to the hospital database) were thought to have PsA clinically, all fulfilling the CASPAR criteria for PsA
• 6 of 93 did not have psoriasis or family history of psoriasis and no historical features or clinical signs of psoriasis on interview and examination
• Extrapolating from data of those people actually examined, the estimated (corrected) prevalence was 13.8% (95% confidence interval 7.1-24.1%)

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