Rheumatology

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No increased occurrence of ischemic heart disease prior to the onset of rheumatoid arthritis: Results from two Swedish population-based rheumatoid arthritis cohorts
Arthritis & Rheumatism, 09/30/09

Holmqvist ME et al. – Shared risk factors or susceptibilities for RA and IHD are likely to contribute less than RA-related factors to the increased occurrence of IHD in patients with manifest RA.

• We assessed the prevalence of a history of IHD, myocardial infarction (MI), and angina pectoris before the onset of RA symptoms in 2 large population-based case-control studies
• Patients with newly diagnosed RA according to the criteria of the American College of Rheumatology were included as cases
• Information on IHD, MI, and angina pectoris was obtained from the nationwide Hospital Discharge Register and from self reports

• We could not detect any increased occurrence of IHD, MI, or angina pectoris before the onset of symptoms of RA, regardless of whether data on IHD were obtained from the Hospital Discharge Register or were self reported
• As detected in the Hospital Discharge Register, the OR for IHD overall was 1.0, the OR for MI was 1.0, and the OR for angina pectoris was 1.0

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