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Single-nucleotide polymorphisms p53G72C and Mdm2T309G in patients with psoriasis, psoriatic arthritis, and SAPHO syndrome
Rheumatology International, 10/15/09
Assmann G et al. – SAPHO syndrome may be linked to an imbalance between MDM2 and p53 regulation with a “weak” p53–response associated with the Mdm2 SNP 309 G allele. In contrast, the p53 network does not seem to play a major role in pathogenesis of Ps or PsA.
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Today in Other Arthritis...keeping you current
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