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See Latest ArticlesFibril protein fragmentation pattern in systemic AL-amyloidosis
The Journal of Pathology, 09/24/09
Enqvist S et al. – The result clearly demonstrates that the fragmentation pattern was similar in amyloid of different organs in one patient but differed greatly between patients. Full–length, N–, and C–terminal fragments were detected with the three antisera. The results strongly support the hypothesis that proteolytic cleavage occurs after fibril formation.
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