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Validation of the knee injury and osteoarthritis outcome score (KOOS) for the treatment of focal cartilage lesions
Osteoarthritis and Cartilage , 09/24/09
Bekkers JEJ et al. – This study illustrates the validity and reliability of the KOOS in measuring the clinical condition of patients after treatment of focal cartilage lesions. This study provides a basis for the use of the KOOS for future clinical research in cartilage repair.
Methods- 40 patients (mean age 35 ± 12 years) treated for a focal cartilage lesion in the knee
- Test–retest data collected with intermediate period of 2 days
- Patients completed the Dutch KOOS and complementary questionnaires to evaluate the clinimetric properties of the KOOS in terms of internal consistency (Cronbach's alpha), reliability [intra-class-correlation (ICC) and Bland and Altman plots], construct validity (Spearman's rank correlation), floor and ceiling effects and responsiveness
- Cronbach's alpha of the KOOS subdomains and total score ranged from 0.74 to 0.96.
- Overall ICC of the KOOS was 0.97 (subscales ranged from 0.87 to 0.95)
- Bland and Altman plots showed small individual variance between two assessments in time
- Spearman's rank correlations between the subscales of the KOOS and representative subscales of the SF-36
- Lysholm and EQ-5D were high to moderate ranging from 0.43 to 0.70
- No floor effect observed while the largest observed ceiling effect was 10.3%
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