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Recommendations on therapy using interleukin-1beta-blocking agents
Zeitschrift für Rheumatologie, 10/07/09
Manger B et al. – The efficacy of the fusion protein rilonacept (RIC) and the monoclonal antibody canakinumab in the treatment of CAPS has been proven by randomized, placebo–controlled trials. In the US, RIL was recently approved by the FDA for the treatment of CAPS under the "Orphan Drug Status".
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