Rheumatology Medical News about Fibromyalgia Medication Therapy Management

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Current progress in the pharmacological therapy of fibromyalgia
Expert Opinion on Investigational Drugs, 09/18/09

Rao SG – Recent research advances highlight a critical role for aberrant central pain processing in FM, and, consistent with these data, the first three drugs approved by the FDA for FM over the past 2 years have a predominantly central mode of action. The first drug, pregabalin, may counteract central pain transmission by inhibiting presynaptic release of excitatory neurotransmitters, including substance P and glutamate. The serotonin–norepinephrine reuptake inhibitors duloxetine and milnacipran have been approved more recently and are believed to reduce pain by increasing serotonin and norepinephrine concentrations in descending inhibitory pain pathways. Agents with multiple other mechanisms of action are in development and promise an assortment of therapeutic options for this complex disorder in the near future.

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Sexual disorder improvement: a target or a way in treatment of fibromyalgia. A case report and brief review
Modern Rheumatology, 10/07/09 Relevance Score: 87%

Review: limited evidence that psychological therapies are of benefit for adults with chronic pain
Evidence-Based Mental Health, 10/28/09 Relevance Score: 86%

Accuracy of reporting current medications by cancer patients presenting to an emergency center
Supportive Care in Cancer, 11/11/09 Relevance Score: 81%

Fibromyalgia: Influence of Depressive Symptoms on the Outcome after Rehabilitation
Die Rehabilitation, 10/29/09 Relevance Score: 80%

Fibromyalgia and Myofascial Pain Syndrome - A Dilemma
Indian Journal of Anaesthesia, 10/22/09 Relevance Score: 80%