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Differences in radiographic features of knee osteoarthritis in African-Americans and Caucasians: The Johnston County Osteoarthritis Project
Osteoarthritis and Cartilage , 09/18/09

Braga L et al. – Compared to Caucasians, AAs were more likely to have more severe TF–OA,; tri–compartmental disease; and lateral JSN. Further research to clarify the discrepancy between radiographic features in OA among races appears warranted.

Methods

Multiple logistic regression was used to evaluate cross–sectional associations between race and TF–OA and the presence, severity and location of individual radiographic features of TFJ–OA (osteophytes, joint space narrowing [JSN], sclerosis and cysts) and PFJ–OA (osteophytes, JSN and sclerosis), using data from the Johnston County Osteoarthritis Project. Proportional odds models (POR) assessed severity of TF–OA, TFJ and PFJ osteophytes, and JSN, adjusting for confounders

Results

Among 3,187 participants (32.5% AAs; 62% women; mean age 62 years), 6,300 TFJ and 1,957 PFJ were included
Compared to Caucasians, AA men were more likely to have TF–OA (adjusted Odds Ratio [aOR] = 1.36; 95% CI, 1.00–1.86); tri–compartmental TFJ and PFJ osteophytes (aOR = 3.06; 95%CI = 1.96–4.78), and TFJ and PFJ sclerosis
AA women were more likely than Caucasian to have medial TFJ and tri–compartmental osteophytes (aOR = 2.13; 1.55– 2.94), and lateral TFJ sclerosis
AAs had more severe TF–OA than Caucasians (aPOR = 2.08; 95% CI, 1.19–3.64 for men; aPOR = 1.56; 95% CI, 1.06–2.29 for women) and were more likely to have lateral TFJ JSN

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