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See Latest ArticlesRandomized placebo-controlled crossover trial of tadalafil in Raynaud's phenomenon secondary to systemic sclerosis
Journal of Rheumatology, 09/16/09
Schiopu Eet al. – Tadalafil appears to be safe and well tolerated but lacks efficacy in comparison to placebo as a treatment for RP secondary to SSc.
Methods- Prospective, randomized, double-blind, placebo-controlled, crossover study
- Oral tadalafil at a fixed dose of 20 mg daily vs placebo
- Period of 4 weeks
- Women with RP secondary to SSc
- 39 subjects completed the study and were evaluable
- No statistically significant differences in Raynaud Condition Score (RCS), frequency of RP episodes, or duration of RP episodes between groups
- Placebo response was confounding factor
- Tadalafil well tolerated
Today in Clinical Pharmacology...keeping you current
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Malignancy-associated multicentric reticulohistiocytosis
Rheumatology International, 12/20/09
Long-term outcome of systemic sclerosis-associated pulmonary arterial hypertension treated with bosentan as first-line monotherapy followed or not by the addition of prostanoids or sildenafil
Rheumatology, 12/18/09
Nicotine-patch therapy on mucocutaneous lesions of Behcet's disease: A case series
Rheumatology, 12/18/09
Today in Connective Tissue Dz...keeping you current
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Long-term outcome of systemic sclerosis-associated pulmonary arterial hypertension treated with bosentan as first-line monotherapy followed or not by the addition of prostanoids or sildenafil
Rheumatology, 12/18/09
Rheumatic heart disease and its control in the Pacific
Expert Review of Cardiovascular Therapy , 12/15/09
Is There a Role for B-cell Depletion as Therapy for Scleroderma? A Case Report and Review of the Literature
Seminars in Arthritis and Rheumatism, 12/15/09
Today in Vasculitic Syndromes...keeping you current
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Wegeners granulomatosis detected initially by integrated 18F-fluorodeoxyglucose positron emission tomography/computed tomography
Modern Rheumatology, 12/20/09
Bowel perforations in a patient affected by Churg–Strauss syndrome under high-dose steroid treatment: will alternative drugs reduce risk of surgery
Rheumatology International, 12/20/09
Is bioptic assurance reasonable in patients with Sjogren’s syndrome
Zeitschrift für Rheumatologie, 12/19/09
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