Rheumatology

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Impact of primary Sjögren's syndrome on smell and taste: effect on quality of life
Rheumatology, 09/15/09

Kamel UF et al. – Clinically important impairment of chemosensory perception occurred in the SS group compared with age- and gender-matched controls. Assessment using SF-12 suggests that this impairment contributed to the reduced health-related QoL that characterized these individuals

• 27 participants with SS
• 37 controls
• Cohort-matched, prospective, cross-sectional study
• Smell and taste thresholds measured using standardized, validated tests
• QoL assessed by Short Form 12 (SF-12)

• Smell threshold was reduced by 1 point in SS group compared with controls
• Taste threshold was reduced by 3.5 points in SS group compared with controls
• The physical and mental components of SF-12 were reduced by 14.2 points and 7.5 points, respectively, in SS group compared with controls
• Taste threshold was significantly correlated with physical and the mental components of SF-12
• Smell threshold correlated with the physical but not the mental component (r = 0.154; P = 0.222) of SF-12

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